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Invitrogen
PACAP Receptor Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA3-213
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
C-terminal of rat PAC1 (503-523) CLSKSSSQLRMSSLPADNLAT coupled to KLH
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
PA3-213 detects PACAP type 1A receptor in rat and mouse samples.
PA3-213 has successfully been used in Western blot and immunohistochemical (paraffin) procedures.
The PA3-213 immunogen is a synthetic peptide corresponding to the C-terminal of rat PAC1 (503-523) CLSKSSSQLRMSSLPADNLAT coupled to KLH
Target Information
This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Alternative splicing of two exons of this gene generates four major splice variants, but their full-length nature has not been determined. PACAP receptor type 1 expression has been documented in adipose, adrenal, bone, brain, colon, ganglion, heart, lung, ovary, pancreas, placenta, spleen, and uterus. ESTs have been isolated from brain and nerve libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADCYAP receptor type 1; ADCYAP1 R1; ADCYAP1R 1; adenylate cyclase activating polypeptide 1 (pituitary) receptor type I; adenylate cyclase activating polypeptide 1 receptor 1; adenylate cyclase activating polypeptide 1 receptor type 1; adenylate cyclase activating polypeptide 1 type 1 receptor; PAC 1; PAC1 receptor; Pac1 receptors; PACAP R 1; PACAP Receptor; PACAP type I receptor; PACAP type IA receptor; PACAP-R-1; PACAP-R-1A; PACAP/VIP receptors; PACAP1 R; PACAP1 receptor; pituitary adenylate cyclase activating polypeptide 1 receptor (1); pituitary adenylate cyclase activating polypeptide receptor; pituitary adenylate cyclase-activating polypeptide type IA receptor; pvr1; unnamed protein product
Gene Aliases: 2900024I10Rik; PAC1; PAC1-R; PAC1R; PACAP-R1; PACAP-R1A; PACAP1-R; PACAPR1; PACAPR1A
UniProt ID: (Rat) P32215, (Mouse) P70205
Entrez Gene ID: (Rat) 24167, (Mouse) 11517
pituitary adenylate cyclase-activating polypeptide receptor activity
transmembrane signaling receptor activity
G-protein coupled receptor activity
vasoactive intestinal polypeptide receptor activity
adenylate cyclase binding
G-protein coupled peptide receptor activity
peptide hormone binding
small GTPase binding
protein binding
neuropeptide binding
cAMP biosynthetic process
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
response to xenobiotic stimulus
positive regulation of calcium ion transport into cytosol
response to estradiol
multicellular organismal response to stress
response to ethanol
cAMP metabolic process
development of primary female sexual characteristics
positive regulation of small GTPase mediated signal transduction
positive regulation of inositol phosphate biosynthetic process
regulation of cellular response to oxidative stress
cAMP/PKA signal transduction
positive regulation of cAMP/PKA signal transduction
negative regulation of response to reactive oxygen species
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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