Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 3
PACRG Antibody (H00135138-D01P) in WB
Western Blot analysis of PACRG expression in transfected 293T cell line (H00135138-T02) by PACRG MaxPab polyclonal antibody.
Lane 1: PACRG transfected lysate(29.30 KDa).
Lane 2: Non-transfected lysate.
Lane 1: PACRG transfected lysate(29.30 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00135138-D01P
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PACRG (NP_001073847.1, 1 a.a. approximately 257 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MVAEKETLSL NKCPDKMPKR TKLLAQQPLP VHQPHSLVSE GFTVKAMMKN SVVRGPPAAG AFKERPTKPT AFRKFYERGD FPIALEHDSK GNKIAWKVEI EKLDYHHYLP LFFDGLCEMT FPYEFFARQG IHDMLEHGGN KILPVLPQLI IPIKNALNLR NRQVICVTLK VLQHLVVSAE MVGKALVPYY RQILPVLNIF KNMNVNSGDG IDYSQQKREN IGDLIQETLE AFERYGGENA FINIKYVVPT YESCLLN
Target Information
PACRG is a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: FLJ32724; Hypertension-related protein 1-like protein; Molecular chaperone/chaperonin-binding protein; PARK2 co-regulated; PARK2 coregulated gene protein; parkin co-regulated gene protein; Parkin coregulated gene protein; Parkin coregulated gene protein homolog; RP3-495O10.2
Gene Aliases: 1700008H23Rik; GLUP; HAK005771; PACRG; PARK2CRG
UniProt ID: (Human) Q96M98, (Mouse) Q9DAK2
Entrez Gene ID: (Human) 135138, (Mouse) 69310
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support