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Invitrogen
PACRG Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Product Details
PA5-66834
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human PACRG. Recombinant protein control fragment (Product #RP-107490).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2664440
Product Specific Information
Immunogen sequence: AFKERPTKPTA FRKFYERGDF PIALEHDSKG NKIAWKVEIE KLDYHHYLPL F
Highest antigen sequence identity to the following orthologs - mouse 94%, rat 29%.
Target Information
PACRG is a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ32724; Molecular chaperone/chaperonin-binding protein; PARK2 co-regulated; PARK2 coregulated gene protein; parkin co-regulated gene protein; Parkin coregulated gene protein; RP3-495O10.2
Gene Aliases: GLUP; HAK005771; PACRG; PARK2CRG
UniProt ID: (Human) Q96M98
Entrez Gene ID: (Human) 135138
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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