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Proteintech
PACSIN2 Polyclonal Antibody
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Product Details
10518-2-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse,
Zebrafish
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PACSIN2 Fusion Protein Ag0809 (180-486 aa encoded by BC008037)
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: PSLNPEQLK KLQDKIEKCK QDVLKTKEKY EKSLKELDQG TPQYMENMEQ VFEQCQQFEE KRLRFFREVL LEVQKHLDLS NVAGYKAIYH DLEQSIRAAD AVEDLRWFRA NHGPGMAMNW PQFEEWSADL NRTLSRREKK KATDGVTLTG INQTGDQSLP SKPSSTLNVP SNPAQSAQSQ SSYNPFEDED DTGSTVSEKD DTKAKNVSSY EKTQSYPTDW SDDESNNPFS STDANGDSNP FDDDATSGTE VRVRALYDYE GQEHDELSFK AGDELTKMED EDEQGWCKGR LDNGQVGLYP ANYVEAIQ (180-486 aa encoded by BC008037)
Target Information
PACSIN 2, a 486 AA phosphoprotein is a novel member of the PACSIN family of cytoplasmic adapter proteins. It is an isoform of PACSIN with a CDC15 N-terminal domain, a C-terminal SH3 domain, 3 conserved regions specific to the PACSIN family, and 3 asn-pro-phe (NPF) motifs, which potentially bind to EH domains. This protein is known to display a ubiquitous expression pattern with the highest levels of expression in brain. Reports suggest that PACSIN 2 participates in the organization of the actin cytoskeleton, the regulation of vesicular traffic. It also participates in endocytic internalization and endocytic receptor recycling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: cytoplasmic phosphoprotein PACSIN2; Protein kinase C and casein kinase substrate in neurons protein 2; RP3-437M21.1; SdpII; syndapin 2; Syndapin II; Syndapin-2; Syndapin-II; syndapin2
Gene Aliases: AI197433; PACSIN2; SDPII
UniProt ID: (Human) Q9UNF0, (Mouse) Q9WVE8
Entrez Gene ID: (Human) 11252, (Mouse) 23970
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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