Immunogen sequence: KADSAVSQEQ LRKLQERVER CAKEAEKTKA QYEQTLAELH RYTPRYMEDM EQAFETCQAA ERQRLLFFKD MLLTLHQHLD LSSSEKFHEL HRDLHQGIEA ASDEEDLRWW RSTHGPGMAM NWPQFEEWSL DTQRTISRKE KGGRSPDEVT LTSIVPTRDG TAPPPQSPGS PGTGQDEEWS DEESPRKAAT GVRVRALYDY AGQEADELSF RAGEELLKMS EEDEQGWCQG QLQSGRIGLY PANYVECVGA; Positive Samples: HepG2, MCF-7, HeLa, Jurkat, Mouse heart, Mouse liver, Mouse lung, Rat liver, Rat brain; Cellular Location: Cell membrane, Cytoplasm, Cytoplasmic side, Peripheral membrane protein
This gene is a member of the protein kinase C and casein kinase substrate in neurons family. The encoded protein is involved in linking the actin cytoskeleton with vesicle formation. Alternative splicing results in multiple transcript variants.
Protein Aliases: Endophilin I; Protein kinase C and casein kinase II substrate protein 3; Protein kinase C and casein kinase substrate in neurons protein 3; SH3 domain-containing protein 6511; syndapin III
Gene Aliases: 4921507A02Rik; 6330413E15Rik; AW413130; PACSIN3; SDPIII
Molecular Function: actin or actin-binding cytoskeletal protein