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Bioss
PAF Polyclonal Antibody
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Product Details
BS-1119R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Chemical
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated PAF.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Platelet Activating Factor (PAF) is a potent phospholipid mediator involved in various biological processes, including inflammation, thrombosis, and allergic reactions. PAF is synthesized by various cell types, including platelets, endothelial cells, and leukocytes. It exerts its effects by binding to the PAF receptor (PAFR), a G-protein coupled receptor, triggering a cascade of intracellular signaling pathways.PAF plays a critical role in the regulation of platelet aggregation, vascular permeability, and leukocyte activation. It is implicated in numerous pathological conditions, such as asthma, sepsis, cardiovascular diseases, and cancer. Due to its significant role in inflammation and immune responses, PAF is considered a valuable target for therapeutic interventions aimed at modulating its activity to treat associated diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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