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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 232 and 481 of Human PAF1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:1000-1:10,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-28560 targets PAF1 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-28560 immunogen is recombinant protein fragment corresponding to a region within amino acids 232 and 481 of Human PAF1.
PAF1, parafibromin (CDC73; MIM 607393), LEO1 (MIM 610507), and CTR9 (MIM 609366) form the PAF protein complex that associates with the RNA polymerase II subunit POLR2A (MIM 180660) and with a histone methyltransferase complex (Rozenblatt-Rosen et al., 2005 [PubMed 15632063]). The PAF complex also has a role in histone monoubiquitination (Zhu et al., 2005 [PubMed 16307923]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
F23149_1; hPAF1; Paf1, RNA polymerase II associated factor, homolog; Pancreatic differentiation protein 2; PD2; RNA polymerase II-associated factor 1 homolog
F23149_1; PAF1; PD2