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PAFR Polyclonal Antibody

View all (8) PTAFR antibodies

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PAFR Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — L1 rat lung lysates, L2 rat brain lysates probed (bs-1478R) Anti-PTAFR Polyclonal, Unconjugated at 1:200 in 4°C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:3000 90 min in 37°C. Predicted band and observed band siz.

PAFR Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Formalin-fixed and paraffin embedded rat colon tissue labeled with Anti-PTAFR Polyclonal Antibody, Unconjugated (bs-1478R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

PAFR Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Formalin-fixed and paraffin embedded rat heart tissue labeled with Anti-PTAFR Polyclonal Antibody, Unconjugated (bs-1478R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

PAFR Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Formalin-fixed and rat lung tissue labeled with Anti-PTAFR Polyclonal Antibody, Unconjugated (bs-1478R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

PAFR Antibody in Flow Cytometry (Flow) — Human 293T cells probed with PAFR Polyclonal Antibody, Unconjugated (bs-1478R) (green) at 1:100 for 30 minutes followed by a PE conjugated secondary antibody compared to unstained cells (blue), secondary only (light blue), and isotype control (orange).

Product Details

BS-1478R

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:2,000	-
Immunohistochemistry (Paraffin) (IHC (P))	1:200	-
Immunohistochemistry (Frozen) (IHC (F))	1:100-1:500	-
Immunocytochemistry (ICC/IF)	1:50-1:200	-
Flow Cytometry (Flow)	1:100	-
ELISA (ELISA)	1:500-1:1,000	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	KLH conjugated synthetic peptide derived from human PAFR, amino acids 231-342. View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	1 mg/mL
Purification	Protein A
Storage buffer	PBS with 50% glycerol, 1% BSA
Contains	0.09% sodium azide
Storage conditions	-20°C

Target Information

PTAFR shows structural characteristics of the rhodopsin gene family and binds platelet-activating factor (PAF). PAF is a phospholipid (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) that has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: PAF receptor; PAF-R; PAFr; Platelet-activating factor receptor

Gene Aliases: PAFR; PTAFR

UniProt ID: (Human) P25105, (Mouse) Q62035, (Rat) P46002

Entrez Gene ID: (Human) 5724, (Mouse) 19204, (Rat) 58949

Molecular Function: G-protein coupled receptor

cytokine production regulation of transcription from RNA polymerase II promoter chemotaxis inflammatory response immune response G-protein coupled receptor signaling pathway parturition response to symbiotic bacterium positive regulation of phospholipase C activity lipopolysaccharide-mediated signaling pathway positive regulation of tumor necrosis factor production inositol trisphosphate biosynthetic process G-protein coupled purinergic nucleotide receptor signaling pathway positive regulation of neutrophil degranulation transcytosis positive regulation of interleukin-6 biosynthetic process positive regulation of translation negative regulation of blood pressure positive regulation of vasoconstriction positive regulation of vasodilation phosphatidylinositol-mediated signaling positive regulation of smooth muscle cell proliferation interferon-gamma-mediated signaling pathway positive regulation of inositol phosphate biosynthetic process cellular response to gravity cellular response to cAMP cellular response to fatty acid response to dexamethasone positive regulation of voltage-gated chloride channel activity positive regulation of leukocyte tethering or rolling positive regulation of sensory perception of pain positive regulation of transcytosis positive regulation of maternal process involved in parturition positive regulation of gastro-intestinal system smooth muscle contraction cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine pattern recognition receptor signaling pathway signal transduction response to lipopolysaccharide

Process(es)

lipopolysaccharide binding lipopolysaccharide receptor activity G-protein coupled receptor activity platelet activating factor receptor activity phospholipid binding G-protein coupled purinergic nucleotide receptor activity mitogen-activated protein kinase binding signal transducer activity