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PAFR Polyclonal Antibody
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Product Details
BS-1478R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human PAFR, amino acids 231-342.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
PTAFR shows structural characteristics of the rhodopsin gene family and binds platelet-activating factor (PAF). PAF is a phospholipid (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) that has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G-protein coupled receptor; PAF receptor; PAF-R; PAFr; Platelet-activating factor receptor; unnamed protein product
Gene Aliases: PAFR; PTAFR
UniProt ID: (Human) P25105, (Mouse) Q62035, (Rat) P46002
Entrez Gene ID: (Human) 5724, (Mouse) 19204, (Rat) 58949
lipopolysaccharide binding
lipopolysaccharide receptor activity
G-protein coupled receptor activity
platelet activating factor receptor activity
protein binding
phospholipid binding
G-protein coupled purinergic nucleotide receptor activity
signal transducer activity
mitogen-activated protein kinase binding
G-protein coupled receptor
chemotaxis
inflammatory response
immune response
signal transduction
G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
lipopolysaccharide-mediated signaling pathway
response to lipopolysaccharide
inositol trisphosphate biosynthetic process
G-protein coupled purinergic nucleotide receptor signaling pathway
cytokine production
pattern recognition receptor signaling pathway
positive regulation of phospholipase C activity
phosphatidylinositol-mediated signaling
positive regulation of inositol phosphate biosynthetic process
positive regulation of voltage-gated chloride channel activity
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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