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Product Details
15583-1-AP
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:1,000 | - |
Immunohistochemistry (IHC) |
Assay-dependent | View 1 publication 1 publication |
Immunocytochemistry (ICC/IF) |
1:10-1:100 | - |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
PAIP2 Fusion Protein Ag7119 (1-127 aa encoded by BC001716) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.27 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Product Specific Information
Immunogen sequence: MKDPSRSST SPSIINEDVI INGHSHEDDN PFAEYMWMEN EEEFNRQIEE ELWEEEFIER CFQEMLEEEE EHEWFIPARD LPQTMDQIQD QFNDLVISDG SSLEDLVVKS NLNPNAKEFV PGVKYGNI (1-127 aa encoded by BC001716)
Target Information
Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: MGC72018; PABC1-interacting protein 2; PABP-interacting protein 2; PAIP-2; poly(A)-binding protein-interacting protein 2; polyA-binding protein-interacting protein 2; polyadenylate-binding protein interacting protein 2; Polyadenylate-binding protein-interacting protein 2
Gene Aliases: 2310050K10Rik; AU045972; HSPC218; PAIP-2; PAIP2; PAIP2A
UniProt ID: (Human) Q9BPZ3, (Mouse) Q9D6V8, (Rat) Q6AXZ0
Entrez Gene ID: (Human) 51247, (Mouse) 67869, (Rat) 361309
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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