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Proteintech
PAIP2 Polyclonal Antibody
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Product Details
15583-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PAIP2 Fusion Protein Ag7119 (1-127 aa encoded by BC001716)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MKDPSRSST SPSIINEDVI INGHSHEDDN PFAEYMWMEN EEEFNRQIEE ELWEEEFIER CFQEMLEEEE EHEWFIPARD LPQTMDQIQD QFNDLVISDG SSLEDLVVKS NLNPNAKEFV PGVKYGNI (1-127 aa encoded by BC001716)
Target Information
Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: MGC72018; PABC1-interacting protein 2; PABP-interacting protein 2; PAIP-2; poly(A)-binding protein-interacting protein 2; polyA-binding protein-interacting protein 2; polyadenylate-binding protein interacting protein 2; Polyadenylate-binding protein-interacting protein 2
Gene Aliases: 2310050K10Rik; AU045972; HSPC218; PAIP-2; PAIP2; PAIP2A
UniProt ID: (Human) Q9BPZ3, (Mouse) Q9D6V8, (Rat) Q6AXZ0
Entrez Gene ID: (Human) 51247, (Mouse) 67869, (Rat) 361309
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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