Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This antibody is predicted to react with mouse, rat, chicken and cow based on sequence homology.
Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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