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Product Details
PA5-57476
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PAIP2. Recombinant protein control fragment (Product #RP-96837).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2645178
Product Specific Information
Immunogen sequence: IPARDLPQTM DQIQDQFNDL VISDGSSLED LVVKSNLNPN A
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC72018; PABC1-interacting protein 2; PABP-interacting protein 2; polyA-binding protein-interacting protein 2; Polyadenylate-binding protein-interacting protein 2
Gene Aliases: HSPC218; PAIP-2; PAIP2; PAIP2A
UniProt ID: (Human) Q9BPZ3
Entrez Gene ID: (Human) 51247
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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