Invitrogen
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
0.5-2 µg/mL | View 1 publication 1 publication |
Immunohistochemistry (IHC) |
10 µg/mL | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
A 14 amino acid peptide from near the amino terminus of human PAK2. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS |
Contains |
0.02% sodium azide |
Storage conditions |
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C |
RRID |
AB_2571863 |
A suggested positive control is Jurkat cell lysate.
PA5-20254 can be used with blocking peptide PEP-0390.
PAK2 (serine/threonine-protein kinase PAK2) is a serine/threonine kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis, or proliferation. It acts as a downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformation change and a subsequent autophosphorylation on several serine and/or threonine residues. Full-length PAK2 stimulates cell survival and cell growth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-t-PAK2; gamma pak; Gamma-PAK; OPHN3; p21 (CDKN1A)-activated kinase 2; p21 protein (Cdc42/Rac)-activated kinase 2; p21-activated kinase 2; p27; p34; p58; PAK alpha; PAK beta; PAK gamma; PAK-2; PAK-2p27; PAK-2p34; PAK3; PAK65; S6/H4 kinase; Serine/threonine-protein kinase PAK 2
Gene Aliases: 5330420P17Rik; A130002K10Rik; AI836325; D16Ertd269e; gamma-PAK; mKIAA4182; PAK-2; PAK2; PAK65; PAKgamma
UniProt ID: (Human) Q13177, (Mouse) Q8CIN4, (Rat) Q64303
Entrez Gene ID: (Human) 5062, (Mouse) 224105, (Rat) 29432
Molecular Function:
non-receptor serine/threonine protein kinase
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