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          • Primary Antibodies ›
          • PAN2 Antibodies

          Invitrogen

          PAN2 Polyclonal Antibody

          View all (4) PAN2 antibodies

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          Cite PAN2 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          PAN2 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          PAN2 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          PAN2 Antibody (PA5-31079) in WB

          Western Blot using PAN2 Polyclonal Antibody (Product # PA5-31079). Sample (30 µg of whole cell lysate). Lane A: Jurkat . 5% SDS PAGE. PAN2 Polyclonal Antibody (Product # PA5-31079) diluted at 1:1,000. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          PAN2 Antibody in Western Blot (WB)
          PAN2 Polyclonal Antibody

          Product Details

          PA5-31079

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein encompassing a sequence within the C-terminus region of human PAN2. The exact sequence is proprietary.
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          0.1M tris glycine, pH 7, with 20% glycerol

          Contains

          0.01% thimerosal

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2548553

          Product Specific Information

          Recommended positive controls: Jurkat.

          Predicted reactivity: Mouse (99%), Rat (98%), Chicken (93%), Bovine (98%).

          Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

          Target Information

          This gene encodes a coregulator for the alpha and beta estrogen receptors and the orphan nuclear receptor NR1D2. The protein localizes to the nucleus, and is thought to have both coactivator and corepressor functions. Its interaction with nuclear receptors is independent of the AF2 domain on the receptors, which is known to regulate interaction with other coreceptors. Two alternatively spliced transcript variants for this gene have been described. However, the full length nature of one of the variants has not been determined.

          ⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Inactive ubiquitin carboxyl-terminal hydrolase 52; PAB-dependent poly(A)-specific ribonuclease subunit 2; PAB-dependent poly(A)-specific ribonuclease subunit PAN2; PAB1P-dependent poly(A)-nuclease; PAB1P-dependent poly(A)-specific ribonuclease; PABP-dependent poly(A) nuclease 2; PAN deadenylation complex catalytic subunit 2; PAN deadenylation complex subunit 2; PAN2 poly(A) specific ribonuclease subunit homolog; PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Poly(A)-nuclease deadenylation complex subunit 2; ubiquitin specific peptidase 52; ubiquitin specific protease 52; unnamed protein product

          View more View less

          Gene Aliases: KIAA0710; PAN2; USP52

          View more View less

          UniProt ID: (Human) Q504Q3

          View more View less

          Entrez Gene ID: (Human) 9924

          View more View less

          Function(s)
          3'-5'-exoribonuclease activity nucleic acid binding nuclease activity exonuclease activity poly(A)-specific ribonuclease activity thiol-dependent ubiquitin-specific protease activity protein binding hydrolase activity metal ion binding
          Process(es)
          nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay nuclear-transcribed mRNA poly(A) tail shortening mRNA processing positive regulation of cytoplasmic mRNA processing body assembly
          It has to be done as per old AB suggested Products section.

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