This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is expressed most abundantly in the liver.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Hallervorden-Spatz syndrome; hPanK; hPanK2; hPanK3; mPank; mPanK3; PANK1/2/3; PANK3; Pantothenate kinase 1; pantothenate kinase 2 (Hallervorden-Spatz syndrome); Pantothenate kinase 2, mitochondrial; Pantothenate kinase 3; Pantothenic acid kinase 1; Pantothenic acid kinase 2; Pantothenic acid kinase 3
Gene Aliases: 4933409I19Rik; AI642621; C20orf48; HARP; HSS; NBIA1; PANK; PANK1; Pank1b; PANK2; PANK3; PKAN