Immunogen sequence: ALDGVVKRAV ASQPDSVDAA ERAEKFRQKY WNKLQTLRQQ PFAYGTLTVR SLLDTREHCL NEFNFPDPYS KVKQRENGVA LRCFPGVVRS LDALGWEERQ LALVKGLLAG NVFDWGAKAV SAVLESDPYF
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 91%.
This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is most abundant in muscle but is expressed in all tissues.
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Protein Aliases: 4'-phosphopantetheine phosphatase; DKFZp547M242; FLJ10782; hPanK4; Pantothenate kinase; Pantothenate kinase 4; Pantothenic acid kinase 4
Gene Aliases: PANK4
UniProt ID: (Human) Q9NVE7
Entrez Gene ID: (Human) 55229