|Tested species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide: S(399) P W S E L E F Q F P D D K D P V W E F(418)|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:250-1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-4314 detects the PAPK protein in mouse samples.
PA1-4314 has been successfully used in Western blot procedures.
The PA1-4314 immunizing peptide corresponds to amino acid residues 399-418 of the mouse PAPK protein.
A novel protein kinase, polyploidy-associated protein kinase (PAPK) is a new member of the Ste20/germinal center kinase family that modulates cytoskeletal organization and cell survival. Activation of a death signal transduction pathway may result in the stimulation of the PAPK promoter, which leads to increased PAPK expression and provides a negative feedback signal that prevents cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.