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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 351 of Human PAPSS1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-28568 targets PAPSS1 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-28568 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 351 of Human PAPSS1.
Three-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS) is the sulfate donor cosubstrate for all sulfotransferase (SULT) enzymes (Xu et al., 2000 [PubMed 10679223]). SULTs catalyze the sulfate conjugation of many endogenous and exogenous compounds, including drugs and other xenobiotics. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2 (MIM 603005).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
3-prime-phosphoadenosine 5-prime-phosphosulfate synthase 1; adenylyl-sulfate kinase; ATPSK1; bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1; PAPS synthase 1; PAPSS; PAPSS 1; SK 1; sulfate adenylyltransferase; sulfurylase kinase 1
ATPSK1; PAPSS; PAPSS1; SK1