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Invitrogen
PAR6 Polyclonal Antibody
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Product Details
PA5-18233
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (GSRIRGDGSGFSL) corresponding to the C-terminus amino acids of PARD6A (aa 334-346).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 domain and a semi-Cdc42/Rac interactive binding domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: PAR-6; PAR-6 alpha; par-6 partitioning defective 6 homolog alpha; PAR6C; Partitioning defective 6 homolog alpha; partitioning-defective protein 6; Tax interaction protein 40; Tax-interacting protein 40; TIP-40
Gene Aliases: PAR-6A; PAR6; PAR6A; PAR6alpha; PAR6C; PARD6A; TAX40; TIP-40
UniProt ID: (Human) Q9NPB6
Entrez Gene ID: (Human) 50855
centrosome cycle
establishment or maintenance of cell polarity
viral process
establishment or maintenance of epithelial cell apical/basal polarity
cell-cell junction maintenance
positive regulation of protein secretion
cell division
regulation of cellular localization
positive regulation of protein localization to centrosome
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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