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Bethyl Laboratories
PARD3 Polyclonal Antibody
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FIGURE: 1 / 1
PARD3 Antibody (A304-496A) in WB
Detection of human and mouse PARD3 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-PARD3 antibody (Product # A304-496A) (lot A304-496A-1) used for WB at 0.1 µg/mL. Detection: Chemiluminescence with an exposure time of 3 minutes.
Product Details
A304-496A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 1306 to 1356 of human Par-3 Partitioning Defective 3 Homolog.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Rat
Target Information
This gene encodes a member of the kinesin 4 or subfamily of kinesin related proteins. This subfamily is also referred to as the chromokinesins. The encoded protein is an ATP dependent microtubule-based motor protein that is involved in the intracellular transport of membranous organelles. This protein also associates with condensed chromosome arms and may be involved maintaining chromosome integrity during mitosis. This protein may also be involved in the organization of the central spindle prior to cytokinesis. A pseudogene of this gene is found on chromosome X.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ASIP; atypical PKC isotype-specific interacting protein; Atypical PKC isotype-specific-interacting protein; bazooka; CTCL tumor antigen se2-5; Ephrin-interacting protein; FLJ21015; PAR-3; par-3 (partitioning defective 3) homolog; par-3 family cell polarity regulator alpha; par-3 partitioning defective 3 homolog; PAR3-alpha; Partitioning defective 3 homolog; PHIP; protein phosphatase 1, regulatory subunit 118; RP11-406D17.1
Gene Aliases: AA960621; AI256638; ASIP; Baz; D8Ertd580e; Par-3; PAR3; PAR3A; PAR3alpha; PARD-3; PARD3; PARD3A; Phip; PPP1R118; SE2-5L16; SE2-5LT1; SE2-5T2
UniProt ID: (Human) Q96RM6, (Mouse) Q99NH2
Entrez Gene ID: (Human) 56288, (Mouse) 93742
microtubule cytoskeleton organization
apical constriction
protein targeting to membrane
cell cycle
establishment or maintenance of cell polarity
negative regulation of peptidyl-threonine phosphorylation
single organismal cell-cell adhesion
myelination in peripheral nervous system
cell differentiation
positive regulation of myelination
regulation of actin filament-based process
wound healing, spreading of cells
cell division
centrosome localization
regulation of cellular localization
bicellular tight junction assembly
establishment of epithelial cell polarity
protein complex assembly
transforming growth factor beta receptor signaling pathway
protein kinase C-activating G-protein coupled receptor signaling pathway
axonogenesis
asymmetric cell division
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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