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Proteintech
PARP10 Polyclonal Antibody
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Product Details
26072-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PARP10 Fusion Protein Ag23457 (673-1025 aa encoded by BC136542)
Conjugate
Form
Liquid
Concentration
0.39 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: QEEAAALRQ ALTLSLLEQP PLEAEEPPDG GTDGKAQLVV HSAFEQDVEE LDRALRAALE VHVQEETVGP WRRTLPAELR ARLERCHGVS VALRGDCTIL RGFGAHPARA ARHLVALLAG PWDQSLAFPL AASGPTLAGQ TLKGPWNNLE RLAENTGEFQ EVVRAFYDTL DAARSSIRVV RVERVSHPLL QQQYELYRER LLQRCERRPV EQVLYHGTTA PAVPDICAHG FNRSFCGRNA TVYGKGVYFA RRASLSVQDR YSPPNADGHK AVFVARVLTG DYGQGRRGLR APPLRGPGHV LLRYDSAVDC ICQPSIFVIF HDTQALPTHL ITCEHVPRAS PDDPSGLPGR SPDT (673-1025 aa encoded by BC136542)
Target Information
Poly(ADP-ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP-ribose to histones. PARPs can also function as transcriptional cofactors. Poly(ADP-ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP-ribose to histones. PARPs can also function as transcriptional cofactors (Yu et al., 2005).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADP-ribosyltransferase diphtheria toxin-like 10; ARTD10; FLJ14464; PARP-10; poly (ADP-ribose) polymerase family, member 10; Poly [ADP-ribose] polymerase 10; Protein mono-ADP-ribosyltransferase PARP10
Gene Aliases: ARTD10; PARP10
UniProt ID: (Human) Q53GL7
Entrez Gene ID: (Human) 84875
protein ADP-ribosylation
negative regulation of gene expression
regulation of chromatin assembly
negative regulation of NF-kappaB transcription factor activity
negative regulation of protein import into nucleus, translocation
negative regulation of viral genome replication
negative regulation of fibroblast proliferation
protein poly-ADP-ribosylation
protein auto-ADP-ribosylation
negative regulation of protein K63-linked ubiquitination
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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