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Proteintech
PARP2 Polyclonal Antibody
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Product Details
20555-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
0.21 mg/mL
Amount
31.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
The antibody is specific to PARP2 (C-terminal).
Target Information
This gene encodes polytransferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADP-ribosyltransferase (NAD+, poly(ADP-ribose) polymerase)-like 2; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 2; ADP-ribosyltransferase (NAD+; poly(ADP-ribose) polymerase)-like 2; ADP-ribosyltransferase diphtheria toxin-like 2; ADPRT-2; ARTD2; DNA ADP-ribosyltransferase PARP2; HGNC:272; hPARP-2; mPARP-2; NAD(+) ADP-ribosyltransferase 2; pADPRT-2; parp 2; PARP-2; poly (ADP-ribose) polymerase family, member 2; poly (ADP-ribosyl) transferase-like 2; Poly [ADP-ribose] polymerase 2; poly(ADP-ribose) polymerase 2; Poly[ADP-ribose] synthase 2; poly[ADP-ribose] synthetase 2; Protein poly-ADP-ribosyltransferase PARP2; unnamed protein product
Gene Aliases: ADPRT2; ADPRTL2; ADPRTL3; ARTD2; Aspartl2; C78626; pADPRT-2; PARP-2; PARP2
UniProt ID: (Human) Q9UGN5, (Mouse) O88554
Entrez Gene ID: (Human) 10038, (Rat) 290027, (Mouse) 11546
DNA binding
chromatin binding
damaged DNA binding
catalytic activity
NAD+ ADP-ribosyltransferase activity
protein binding
transferase activity
transferase activity, transferring glycosyl groups
nucleotidyltransferase activity
nucleosome binding
poly-ADP-D-ribose binding
NAD DNA ADP-ribosyltransferase activity
NAD+-protein-serine ADP-ribosyltransferase activity
NAD+-protein-aspartate ADP-ribosyltransferase activity
NAD+-protein-glutamate ADP-ribosyltransferase activity
poly-ADP-D-ribose modification-dependent protein binding
protein ADP-ribosylase activity
DNA metabolism protein
DNA repair
base-excision repair
double-strand break repair
cellular response to DNA damage stimulus
DNA ADP-ribosylation
decidualization
positive regulation of cell growth involved in cardiac muscle cell development
protein poly-ADP-ribosylation
protein auto-ADP-ribosylation
protein localization to chromatin
response to oxygen-glucose deprivation
extrinsic apoptotic signaling pathway
hippocampal neuron apoptotic process
DNA repair-dependent chromatin remodeling
protein ADP-ribosylation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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