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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues Q(43) R Q E S K K M P V A G G K A N K(59) of human PARP2.|
|Storage buffer||whole serum|
|Contains||0.02% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:250 - 1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-4280 detects the PARP-2 protein in human samples.
PA1-4280 has been successfully used in Western blot procedures. This antibody detects a ~66 kDa protein representing PARP-2 in 3T3 cell lysate.
PA1-4280 immunizing peptide corresponds to amino acid residues 43-59 of the 62 kDa human PARP-2 protein.
Store at 4°C for 3 months or at -20°C for longer periods.
Poly(ADP-ribose) polymerase 1, (PARP-1) and poly(ADP-ribose) polymerase 2 (PARP-2) catalyze the formation of poly(ADP-ribose) polymers in a DNA-dependent manner. PARP-2 displays automodification properties similar to PARP-1. These act by poly(ADP-ribosylation), which is a post-translational modification of nuclear proteins in response to DNA damage that activates the base excision repair machinery.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ADP-ribosyltransferase (NAD+; poly(ADP-ribose) polymerase)-like 2; ADP-ribosyltransferase diphtheria toxin-like 2; ADPRT-2; hPARP-2; NAD(+) ADP-ribosyltransferase 2; pADPRT-2; poly (ADP-ribose) polymerase 2; poly (ADP-ribose) polymerase family, member 2; poly (ADP-ribosyl) transferase-like 2; poly[ADP-ribose] synthase 2; Poly[ADP-ribose] synthetase 2
ADPRT2; ADPRTL2; ADPRTL3; ARTD2; pADPRT-2; PARP-2; PARP2