Recommended positive controls: HepG2.
Predicted reactivity: Cow: 92%; Dog: 91%; Horse: 100%; Mouse: 77%; Pig: 85%; Rabbit: 100%; Rat: 92%.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
PARP3, poly(ADP-ribosyl)transferase 3, belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This protein is preferentially localized to the daughter centriole throughout the cell cycle.
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Protein Aliases: ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 2; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 3; ADP-ribosyltransferase diphtheria toxin-like 3; ADPRT-3; ADPRT3; ADPRTL2; ADPRTL3; ARTD3; DNA ADP-ribosyltransferase PARP3; IRT1; NAD(+) ADP-ribosyltransferase 3; NAD+ ADP-ribosyltransferase 3; PADPRT-3; PARP-3; poly (ADP-ribose) polymerase family, member 3; Poly [ADP-ribose] polymerase 3; poly(ADP-ribose) synthetase-3; Poly[ADP-ribose] synthase 3; poly[ADP-ribose] synthetase 3; Protein mono-ADP-ribosyltransferase PARP3
Gene Aliases: ADPRT3; ADPRTL2; ADPRTL3; ARTD3; IRT1; PADPRT-3; PARP3
UniProt ID: (Human) Q9Y6F1
Entrez Gene ID: (Human) 10039