Immunogen sequence: QEEGMNAINL PLSPIPFELD PEDTMLEENE VRTMVDPNSR SDPKLQELMK VLIDWINDVL VGERIIVKDL AEDLYDGQVL QKLFEKLESE KLNVAEVTQS EIAQKQKLQT VLEKINETLK LP
The protein encoded by this gene is a transcription factor that contains C2H2-type zinc-fingers. It also contains a positive regulatory domain, which has been found in several other zinc-finger transcription factors including those involved in B cell differentiation and tumor suppression. Studies of the mouse counterpart suggest that this protein may be involved in the development of the central nerve system (CNS), as well as in the pathogenesis of neuronal storage disease. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
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Protein Aliases: Actopaxin; Alpha-parvin; Calponin-like integrin-linked kinase-binding protein; CH-ILKBP; FLJ10793; FLJ12254; Matrix-remodeling-associated protein 2; MXRA2; parvin, alpha
Gene Aliases: CH-ILKBP; MXRA2; PARVA
UniProt ID: (Human) Q9NVD7
Entrez Gene ID: (Human) 55742