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Product Details
PAX2E-212-FITC
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 205-235 on human PAX2 isoform d protein.
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Transcription factor that may have a role in kidney cell differentiation (PubMed:24676634). Has a critical role in the development of the urogenital tract, the eyes, and the CNS.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: optic disc coloboma; paired box gene 2; paired box homeotic gene 2; Paired box protein Pax-2; PAX2
Gene Aliases: FSGS7; Opdc; PAPRS; Pax-2; PAX2
UniProt ID: (Human) Q02962, (Mouse) P32114
Entrez Gene ID: (Human) 5076, (Mouse) 18504, (Rat) 293992
core promoter proximal region sequence-specific DNA binding
DNA binding
protein binding
transcription factor binding
superoxide-generating NADPH oxidase activity
transcription regulatory region DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
C2H2 zinc finger domain binding
sequence-specific DNA binding
urogenital system development
branching involved in ureteric bud morphogenesis
cell fate determination
mesonephros development
neural tube closure
optic cup morphogenesis involved in camera-type eye development
mesenchymal to epithelial transition involved in metanephros morphogenesis
retinal pigment epithelium development
transcription, DNA-templated
transcription from RNA polymerase II promoter
axonogenesis
mesodermal cell fate specification
aging
visual perception
glial cell differentiation
optic nerve development
optic nerve morphogenesis
optic nerve structural organization
vestibulocochlear nerve formation
response to nutrient levels
regulation of metanephros size
ureter maturation
pronephric field specification
inner ear morphogenesis
camera-type eye development
negative regulation of apoptotic process
negative regulation of programmed cell death
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
protein kinase B signaling
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
negative regulation of cytolysis
positive regulation of transcription from RNA polymerase II promoter
pronephros development
brain morphogenesis
stem cell differentiation
positive regulation of epithelial cell proliferation
oxidation-reduction process
mesenchymal to epithelial transition
optic chiasma development
cellular response to hydrogen peroxide
cellular response to retinoic acid
cellular response to glucose stimulus
cellular response to epidermal growth factor stimulus
metanephric mesenchyme development
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
metanephric mesenchymal cell differentiation
nephric duct formation
ureter development
metanephric collecting duct development
metanephric epithelium development
metanephric distal convoluted tubule development
metanephric nephron tubule formation
positive regulation of metanephric glomerulus development
negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
regulation of metanephric nephron tubule epithelial cell differentiation
reactive oxygen species metabolic process
cochlea development
cochlea morphogenesis
positive regulation of branching involved in ureteric bud morphogenesis
negative regulation of mesenchymal cell apoptotic process involved in metanephros development
negative regulation of apoptotic process involved in metanephric collecting duct development
negative regulation of apoptotic process involved in metanephric nephron tubule development
negative regulation of reactive oxygen species metabolic process
positive regulation of metanephric DCT cell differentiation
positive regulation of optic nerve formation
negative regulation of transcription from RNA polymerase II promoter
metanephros development
ureteric bud development
kidney development
regulation of transcription, DNA-templated
multicellular organism development
positive regulation of cell proliferation
cell differentiation
regulation of apoptotic process
regulation of programmed cell death
animal organ development
paramesonephric duct development
renal system development
mesonephric tubule development
mesonephric tubule formation
mesonephric duct development
pancreas development
cellular response to mechanical stimulus
ureter morphogenesis
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