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PA1-108 has been validated for WB on recombinant human Pax4 protein, but may not be suitable for detecting endogenous Pax4.
By immunofluorescence, PA1-108 has been used to stain paraffin-embedded human and mouse pancreatic tissue.
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells.
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Protein Aliases: MGC129960; paired box gene 4; Paired box protein Pax-4; paired domain gene 4
Gene Aliases: KPD; MODY9; Pax-4; Pax4
UniProt ID: (Mouse) P97341