PA5-27253 targets PAX7 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-27253 immunogen is synthetic peptide corresponding to a region within amino acids 456 and 520 of Human PAX7.
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This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: HUP1; paired box homeotic gene 7; Paired box protein Pax-7; paired domain gene 7; PAX7 transcriptional factor; PAX7B; RMS2
Gene Aliases: HUP1; PAX7; PAX7B; RMS2
UniProt ID: (Human) P23759
Entrez Gene ID: (Human) 5081