|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 456 and 520 of Human PAX7|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27253 targets PAX7 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-27253 immunogen is synthetic peptide corresponding to a region within amino acids 456 and 520 of Human PAX7.
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HUP1; paired box homeotic gene 7; Paired box protein Pax-7; paired domain gene 7; PAX7 transcriptional factor; PAX7B; RMS2
Gene Aliases: HUP1; PAX7; PAX7B; RMS2
UniProt ID: (Human) P23759
Entrez Gene ID: (Human) 5081
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