Active Motif

PBRM1 Polyclonal Antibody

View all (16) PBRM1 antibodies

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PBRM1 Antibody in Western Blot (WB) — PBRM1 antibody (pAb) tested by Western blot. Detection of PBRM1 by Western blot. The analysis was performed using 40 µg A-431 nuclear extract and PBRM1 (pAb) at a 1:500 dilution.

PBRM1 Antibody in ChIP-sequencing (ChIP-Seq) — PBRM1 antibody (pAb) tested by ChIP-Seq. Chromatin immunoprecipitation (ChIP) was performed using the ChIP-IT® High Sensitivity Kit (Cat. No. 53040) with 30 µg of chromatin from mouse liver and 4 µg PBRM1 antibody. ChIP DNA was sequenced on the Illumina HiSeq and 3.9 million sequence tags were mapped to identify PBRM1 binding sites.

Product Details

61381

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:1,000	-
ChIP-sequencing (ChIP-Seq)	4 µg	-

Product Specifications
Species Reactivity	Human, Mouse
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	This antibody was raised against a peptide within the N-terminal region of human PBRM1. View immunogen
Conjugate	Unconjugated
Form	Liquid
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.5, with 30% glycerol
Contains	0.035% sodium azide
Storage conditions	-20° C, Avoid Freeze/Thaw Cycles
RRID	AB_2793612

Target Information

Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 2310032M22Rik; BAF180; BRG1-associated factor 180; hPB1; Polybromo-1D; Protein polybromo-1

Gene Aliases: 2610016F04Rik; AI507524; BAF180; PB1; PBRM1

UniProt ID: (Human) Q86U86

Entrez Gene ID: (Human) 55193, (Mouse) 66923

Molecular Function: chromatin/chromatin-binding, or -regulatory protein

chromatin remodeling transcription, DNA-templated regulation of transcription, DNA-templated mitotic nuclear division negative regulation of cell proliferation covalent chromatin modification placenta development blood vessel remodeling heart morphogenesis epicardium-derived cardiac endothelial cell differentiation heart development chromatin modification positive regulation of transcription, DNA-templated cardiac vascular smooth muscle cell development vasculogenesis involved in coronary vascular morphogenesis

Process(es)

DNA binding chromatin binding protein binding