PBX4 encodes a member of the pre-B cell leukemia transcription factor family. These proteins are homeobox proteins that play critical roles in embryonic development and cellular differentiation both as Hox cofactors and through Hox-independent pathways. The encoded protein contains a homeobox DNA-binding domain, but specific functions of the protein have not been determined. Alternatively spliced transcript variants have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor 4; Homeobox protein PBX4; pre-B-cell leukemia homeobox 4; Pre-B-cell leukemia transcription factor 4
Gene Aliases: 2410015M21Rik; AI429113; AW045266; Edg4; PBX4
Molecular Function: homeodomain transcription factor