Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. Tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling.
Protein Aliases: Hematopoietic PBX-interacting protein; pre-B-cell leukemia homeobox interacting protein 1; Pre-B-cell leukemia transcription factor-interacting protein 1
Gene Aliases: HPIP; PBXIP1
UniProt ID: (Human) Q96AQ6
Entrez Gene ID: (Human) 57326