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Proteintech
PCDH15 Polyclonal Antibody
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Product Details
20719-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Amount
60 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Target Information
PCDH15 is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. PCDH15 consists of a signal peptide, 11 extracellular calcium-binding domains, a transmembrane domain and a unique cytoplasmic domain. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene have been associated with hearing loss, which is consistent with its location at the Usher syndrome type 1F (USH1F) critical region on chromosome 10.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ames waltzer; cadherin-related family member 15; DKFZp667A1711; PCDH15; protocadherin 15 CD2; protocadherin 15 CD3 isoform; Protocadherin-15; RP11-449J3.2; unnamed protein product
Gene Aliases: av; BB078305; CDHR15; DFNB23; ENSMUSG00000046980; Gm9815; nmf19; PCDH15; USH1F
UniProt ID: (Human) Q96QU1, (Mouse) Q99PJ1
Entrez Gene ID: (Human) 65217, (Rat) 690865, (Mouse) 11994
cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
sensory perception of sound
photoreceptor cell maintenance
inner ear development
sensory perception of light stimulus
equilibrioception
startle response
morphogenesis of an epithelium
actin filament organization
visual perception
locomotory behavior
adult walking behavior
adult locomotory behavior
nonmotile primary cilium assembly
multicellular organism growth
auditory receptor cell differentiation
detection of mechanical stimulus involved in sensory perception of sound
detection of mechanical stimulus involved in equilibrioception
response to calcium ion
righting reflex
auditory receptor cell stereocilium organization
inner ear receptor stereocilium organization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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