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Invitrogen
PCDH15 Polyclonal Antibody
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FIGURE: 1 / 3
PCDH15 Antibody (PA5-47865) in ICC/IF
Immunocytochemistry analysis of PCDH15 in immersion fixed YT human leukemia natural killer-like cell line. Samples were incubated in PCDH15 polyclonal antibody (Product # PA5-47865) using a dilution of 10 µg/mL for 3 hours at room temperature followed by NorthernLights™ 557-conjugated Anti-Sheep IgG Secondary Antibody (red) and counterstained with DAPI (blue). Specific staining was localized to cell surfaces and cytoplasm.
Product Details
PA5-47865
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CHO-derived recombinant human Protocadherin-15 Gln27-Ala1376
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) Protocadherin-1, rhProtocadherin-8, and rhProtocadherin-10 is observed.
Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
Target Information
PCDH15 is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. PCDH15 consists of a signal peptide, 11 extracellular calcium-binding domains, a transmembrane domain and a unique cytoplasmic domain. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene have been associated with hearing loss, which is consistent with its location at the Usher syndrome type 1F (USH1F) critical region on chromosome 10.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cadherin-related family member 15; DKFZp667A1711; PCDH15; Protocadherin-15; RP11-449J3.2; unnamed protein product
Gene Aliases: CDHR15; DFNB23; PCDH15; USH1F
UniProt ID: (Human) Q96QU1
Entrez Gene ID: (Human) 65217
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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