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Proteintech
PCDHA6 Polyclonal Antibody
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Product Details
12853-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PCDHA6 Fusion Protein Ag3493 (711-950 aa encoded by BC036674)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LVLTLLLYT ALRCSAPPTE GACTADKPTL VCSSAVGSWS YSQQRRQRVC SGEGPPKMDL MAFSPSLSPC PIMMGKAENQ DLNEDHDAKP RQPNPDWRYS ASLRAGMHSS VHLEEAGILR AGPGGPDQQW PTVSSATPEP EAGEVSPPVG AGVNSNSWTF KYGPGNPKQS GPGELPDKFI IPGSPAIISI RQEPTNSQID KSDFITFGKK EETKKKKKKK KGNKTQEKKE KGNSTTDNSD Q (711-950 aa encoded by BC036674)
Target Information
This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cadherin-related neuronal receptor 2; cadherin-related neuronal receptor 6; KIAA0345-like 8; PCDH-alpha-6; Protocadherin alpha-6
Gene Aliases: CNR; CNR2; CNRN2; CNRS2; CRNR2; PCDH-ALPHA6; PCDHA6; rCNRv06
UniProt ID: (Human) Q9UN73
Entrez Gene ID: (Human) 56142, (Rat) 393088, (Mouse) 12937
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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