|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 190-217 amino acids from the central region of human PCGF6|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with mouse and rat based on sequence homology.
The protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor. The activity of this protein is found to be regulated by cell cycle dependent phosphorylation. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MBLR; Mel18 and Bmi1-like RING finger; Mel18 and Bmi1-like RING finger protein; PCGF6; Polycomb group RING finger protein 6; RING finger protein 134; RNF134
Gene Aliases: MBLR; PCGF6; RNF134
UniProt ID: (Human) Q9BYE7
Entrez Gene ID: (Human) 84108
Molecular Function: ubiquitin-protein ligase
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