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Abnova
PCLO Polyclonal Antibody, MaxPab™
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Product Details
H00027445-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PCLO (AAH01304.2, 1 a.a. approximately 356 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MKKFRVSLVS KVGKQKYVDL NMLSDSENSQ HLELHEPPKA VDKAKSPGVD PKQLAAELQK VSLQQSPLVL SSVVEKGSHV HSGPTSAGSS SVPSPGQPGS PSVSKKKHGS SKPTDGTKVV SHPITGEIQL QINYDLGNLI IHILQARNLV PRDNNGYSDP FVKVYLLPGR GAEYKRRTKH VQKSLNPEWN QTVIYKSISM EQLKKKTLEV TVWDYDRFSS NDFLGEVLID LSSTAHLDNT PRWYPLKEQT ESIDHGKSHS SQSSQQSPKP SVIKSRSHGI FPDPSKDMQV PTIEKSHSSP GSSKSSSEGH LRSHGPSRSQ SKTSVTQTHL EDAGAAIAAA EAAVQQLRIQ PSKRRK
Target Information
The protein encoded by the PCLO gene is part of the presynaptic cytoskeletal matrix, which is involved in establishing active synaptic zones and in synaptic vesicle trafficking. Variations in this gene have been associated with bipolar disorder and major depressive disorder. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Aczonin; Protein piccolo; unnamed protein product
Gene Aliases: ACZ; KIAA0559; PCH3; PCLO
UniProt ID: (Human) Q9Y6V0
Entrez Gene ID: (Human) 27445
cytoskeleton organization
synaptic vesicle exocytosis
regulation of exocytosis
insulin secretion
protein localization to synapse
maintenance of presynaptic active zone structure
regulation of transport
regulation of biological quality
synaptic vesicle clustering
presynaptic actin cytoskeleton organization
presynapse organization
presynaptic active zone assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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