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Invitrogen
PCSK5 Polyclonal Antibody
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Product Details
PA5-42378
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
C. elegans,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the middle region of human PCSK5
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: CAGAGADGCI NCTEGYFMED GRCVQSCSIS YYFDHSSENG YKSCKKCDIS
Sequence homology: Cow: 100%; Dog: 100%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 79%
Target Information
PCSK5 belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. PCSK5 mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known. The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: PC5; PC6; prohormone convertase 5; Proprotein convertase 5; Proprotein convertase 6; Proprotein convertase subtilisin/kexin type 5; protease PC6; subtilase; Subtilisin/kexin-like protease PC5
Gene Aliases: PC5; PC6; PC6A; PCSK5; SPC6
UniProt ID: (Human) Q92824
Entrez Gene ID: (Human) 5125
kidney development
renin secretion into blood stream
cardiac septum development
signal peptide processing
cell-cell signaling
determination of left/right symmetry
heart development
embryo implantation
anterior/posterior pattern specification
protein processing
peptide hormone processing
viral life cycle
respiratory tube development
nerve growth factor processing
limb morphogenesis
cytokine biosynthetic process
peptide biosynthetic process
embryonic digestive tract development
embryonic skeletal system development
coronary vasculature development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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