Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: YLEHVVVRIT ITHPRRGDLA IYLTSPSGTR SQLLANRLFD HSMEGFKNWE FMTIHCWGER AAGDWVLEVY DTPSQLRNFK TPGKLKEWSL VLYGTSVQPY SPTNEFPKVE RFRYSRVEDP TDD
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
PCSK5 belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. PCSK5 mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known. The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: PC5; PC6; prohormone convertase 5; Proprotein convertase 5; Proprotein convertase 6; Proprotein convertase subtilisin/kexin type 5; protease PC6; subtilase; Subtilisin/kexin-like protease PC5
Gene Aliases: PC5; PC6; PC6A; PCSK5; SPC6
UniProt ID: (Human) Q92824
Entrez Gene ID: (Human) 5125
Molecular Function: serine protease
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