Note: You clicked on an external link, which has been disabled in order to keep your shopping session open.
Western Blot staining of HEK293 lysate overexpressing Human PCSK9 (c-term Myc tagged and loaded in Lane A&C) stained with PA5-18612 at a concentration of 0.5 ug/ml (lane A). Lane C was stained with anti-MYC Tag at a dilution of (1/1000). Lane B was loaded with mock-transfected HEK293 cells and stained using PA5-18612 at a concentration of 1 mg/ml. Primary antibody incubation was performed for 1 hour and detection was performed by chemiluminescence.
|Tested species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (PRYRADEYQPPD) corresponding to the internal amino acids of PCSK9|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||0.1-0.5 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia .
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
convertase subtilisin/kexin type 9 preproprotein; FH3; HCHOLA3; hypercholesterolemia, autosomal dominant 3; NARC-1; NARC1; neural apoptosis regulated convertase 1; PCSK9; proprotein convertase subtilisin/kexin type 9; subtilisin/kexin-like protease PC9
FH3; HCHOLA3; LDLCQ1; NARC-1; NARC1; PC9; PCSK9; PSEC0052