Immunogen sequence: CCHAPGLECK VKEHGIPAPQ EQVTVACEEG WTLTGCSALP GTSHVLGAYA VDNTCVVRSR DVSTTGSTSE GAVTAVAICC RSRHLAQASQ ELQ; Positive Samples: SW480; Cellular Location: Cell surface, Cytoplasm, Endoplasmic reticulum, Endosome, Golgi apparatus, Lysosome
The protein encoded by VBP1 interacts with the Von Hippel-Lindau protein to form an intracellular complex. The encoded protein functions as a chaperone protein, and may play a role in the transport of the Von Hippel-Lindau protein from the perinuclear granules to the nucleus or cytoplasm. Alternative splicing and the use of alternate transcription start sites results in multiple transcript variants encoding different protein isoforms.
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Protein Aliases: convertase subtilisin; convertase subtilisin/kexin type 9 preproprotein; NARC-1; neural apoptosis regulated convertase 1; Neural apoptosis-regulated convertase 1; PC9; Proprotein convertase 9; proprotein convertase PC9; Proprotein convertase subtilisin/kexin type 9; Subtilisin/kexin-like protease PC9
Gene Aliases: AI415265; AI747682; FH3; HCHOLA3; LDLCQ1; NARC-1; NARC1; PC9; PCSK9; PSEC0052