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PCYT2 Polyclonal Antibody

PCYT2 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 5

PCYT2 Antibody (14827-1-AP) in ICC/IF

Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HepG2 cells using 14827-1-AP (PCYT2 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

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Product Details

14827-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

View 3 publications 3 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:20-1:200

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PCYT2 Fusion Protein Ag6616 (1-389 aa encoded by BC000351)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MIRNGRGAA GGAEQPGPGG RRAVRVWCDG CYDMVHYGHS NQLRQARAMG DYLIVGVHTD EEIAKHKGPP VFTQEERYKM VQAIKWVDEV VPAAPYVTTL ETLDKYNCDF CVHGNDITLT VDGRDTYEEV KQAGRYRECK RTQGVSTTDL VGRMLLVTKA HHSSQEMSSE YREYADSFGK CPGGRNPWTG VSQFLQTSQK IIQFASGKEP QPGETVIYVA GAFDLFHIGH VDFLEKVHRL AERPYIIAGL HFDQEVNHYK GKNYPIMNLH ERTLSVLACR YVSEVVIGAP YAVTAELLSH FKVDLVCHGK TEIIPDRDGS DPYQEPKRRG IFRQIDSGSN LTTDLIVQRI ITNRLEYEAR NQKKEAKELA FLEAARQQAA QPLGERDGDF (1-389 aa encoded by BC000351)

Target Information

ECT (ethanolaminephosphate cytidyltransferase) is an important regulatory enzyme in the pathway for phosphatidylethanolamine (PE) biosynthesis. PE functions in cell signalling, membrane fusion, platelet activation, and cell cycle progression. Specialized forms of PE exist as plasmologens, natural cannabinoid anadimade, and glycosylated PE. The ECT enzyme acts in the second of three catalysis steps to produce CDP-ethanolamine from phosphoethanolamine (P-Etn). Study of ECT could help determine the role of plasmologens in disease, specifically lipid disorders such as peroxisomal diseases as well as neuronal degeneration associated with Alzheimer's disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

p75NTR enhances cognitive dysfunction in a mouse Alzheimer's disease model by inhibiting microRNA-210-3p-mediated PCYT2 through activation of NF-κB.

International journal of biological macromolecules

Wei Z,Yang C,Feng K,Guo S,Huang Z,Wang Y,Jian C

Sun Jan 15 00:00:00 UTC 2023

p75NTR enhances cognitive dysfunction in a mouse Alzheimer's disease model by inhibiting microRNA-210-3p-mediated PCYT2 through activation of NF-κB.

International journal of biological macromolecules

Wei Z,Yang C,Feng K,Guo S,Huang Z,Wang Y,Jian C

Sun Jan 15 00:00:00 UTC 2023

p75NTR enhances cognitive dysfunction in a mouse Alzheimer's disease model by inhibiting microRNA-210-3p-mediated PCYT2 through activation of NF-κB.

International journal of biological macromolecules

Wei Z,Yang C,Feng K,Guo S,Huang Z,Wang Y,Jian C

Sun Jan 15 00:00:00 UTC 2023

p75NTR enhances cognitive dysfunction in a mouse Alzheimer's disease model by inhibiting microRNA-210-3p-mediated PCYT2 through activation of NF-κB.

International journal of biological macromolecules

Wei Z,Yang C,Feng K,Guo S,Huang Z,Wang Y,Jian C

Sun Jan 15 00:00:00 UTC 2023

Cancer Malignancy Is Correlated with Upregulation of PCYT2-Mediated Glycerol Phosphate Modification of α-Dystroglycan.

International journal of molecular sciences

Umezawa F,Natsume M,Fukusada S,Nakajima K,Yamasaki F,Kawashima H,Kuo CW,Khoo KH,Shimura T,Yagi H,Kato K

Wed Jun 15 00:00:00 UTC 2022

Metabolic control of T_FH cells and humoral immunity by phosphatidylethanolamine.

Nature

Fu G,Guy CS,Chapman NM,Palacios G,Wei J,Zhou P,Long L,Wang YD,Qian C,Dhungana Y,Huang H,Kc A,Shi H,Rankin S,Brown SA,Johnson A,Wakefield R,Robinson CG,Liu X,Sheyn A,Yu J,Jackowski S,Chi H

Thu Jul 01 00:00:00 UTC 2021

Metabolomic Study on Nude Mice Models of Gastric Cancer Treated with Modified Si Jun Zi Tang via HILIC UHPLC-Q-TOF/MS Analysis.

Evidence-based complementary and alternative medicine : eCAM

Nie S,Zhao Y,Qiu X,Wang W,Yao Y,Yi M,Wang D

Wed Sep 30 00:00:00 UTC 2020

Bioinformatics

Protein Aliases: CTP:phopshoethanolamine cytidylyltransferase; CTP:phosphoethanolamine cytidylyltransferase; Ethanolamine-phosphate cytidylyltransferase; Phosphorylethanolamine transferase

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Gene Aliases: 1110033E03Rik; ET; PCYT2

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UniProt ID: (Human) Q99447, (Rat) O88637, (Mouse) Q922E4

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Entrez Gene ID: (Human) 5833, (Rat) 89841, (Mouse) 68671

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Function(s)

ethanolamine-phosphate cytidylyltransferase activity catalytic activity transferase activity nucleotidyltransferase activity nucleotidyltransferase transferase metabolite interconversion enzyme

Process(es)

phosphatidylethanolamine biosynthetic process phospholipid biosynthetic process lipid metabolic process biosynthetic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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PCYT2 Polyclonal Antibody

PCYT2 Antibody (14827-1-AP) in ICC/IF

Product Details

14827-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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