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Invitrogen
PDC Polyclonal Antibody
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FIGURE: 1 / 2
PDC Antibody (PA5-116596) in IHC (P)
Immunohistochemistry analysis of PDC in paraffin-embedded rat retina. Samples were incubated with PDC Polyclonal antibody (Product # PA5-116596) using a dilution of 1:200 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-116596
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of human PDC (NP_0025883)
Conjugate
Form
Liquid
Concentration
1.33 mg/mL
Amount
133 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: Mouse eye, Rat eye
Immunogen sequence: MEEAKSQSLE EDFEGQATHT GPKGVINDWR KFKLESQDSD SIPPSKKEIL RQMSSPQSRN GKDSKERVSR KMSIQEYELI HKEKEDENCL RKYRRQCMQD MHQKLSFGPR YGFVYELETG KQFLETIEKE LKITTIVVHI YEDGIKGCDA LNSSLTCLAA EYPIVKFCKI KASNTGAGDR FSLDVLPTLL IYKGGELISN FISVAEQFAE EFFAGDVESF LNEYGLLPER EVHVLEHTKI EEEDVE
Target Information
PDC encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. PDC is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 33 kDa phototransducing protein; MBG8.23; MBG8_23; MEKA protein; PDC1; PDC2; PHD; Phosducin; Phototransducing protein, 33 kDa (phosducin); Protein MEKA; PYRUVATE DECARBOXYLASE; pyruvate decarboxylase-1; pyruvate decarboxylase-2; Rod photoreceptor 1; RPR-1
Gene Aliases: 33DPTP; MEKA; Pdc; Rpr-1; Rpr1
UniProt ID: (Mouse) Q9QW08, (Rat) P20942
Entrez Gene ID: (Mouse) 20028, (Rat) 25343
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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