|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 547 and 779 of Human PDE10A|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 20% glycerol|
|Contains||0.025% Proclin 300|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31293 targets PDE10A in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-31293 immunogen is recombinant fragment corresponding to a region within amino acids 547 and 779 of Human PDE10A.
Various cellular responses are regulated by the second messengers cAMP and cGMP. Phosphodiesterases, such as PDE10A, eliminate cAMP- and cGMP-mediated intracellular signaling by hydrolyzing the cyclic nucleotide to the corresponding nucleoside 5-prime monophosphate (Fujishige et al., 2000 [PubMed 10998054]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 5'-cyclic phosphodiesterase 10A; cAMP and cAMP-inhibited cGMP 3'; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A; dJ416F21.1 (phosphodiesterase 10A); HSPDE10A; phosphodiesterase 10A1 (PDE10A1); phosphodiesterase 10A7 (PDE10A7)
Gene Aliases: ADSD2; HSPDE10A; IOLOD; LINC00473; PDE10A; PDE10A19
UniProt ID: (Human) Q9Y233
Entrez Gene ID: (Human) 10846
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