Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
PA1-31128 detects PDE2A from mouse, human, rat samples.
PA1-31128 has been successfully used in immunoprecipitation, Western blot applications.
The PA1-31128 immunogen is: Two synthetic peptides corresponding to the N and C-terminal regions of PDE2A.
PDE2A (phosphodiesterase 2A) is a 100 kD cyclic nucleotide phosphodiesterase (PDE) and three isoforms of PDE2A have been reported (PDE2A1, PDE2A2 and PDE2A3) which arise from a single gene by alternative splicing events. PDE2A can degrade both cAMP and cGMP, but degrades cGMP with greater efficacy. PDE2A is expressed in a variety of tissue types, with greatest expression in the brain, where it is localized in the cerebellum and neocortex. PDE2A has been implicated in penile erectile dysfunction and in the regulation of fluid and inflammatory cell transport across the endothelial cell barrier.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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