Invitrogen
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
0.04-0.4 µg/mL | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:200-1:500 | - |
Immunocytochemistry (ICC/IF) |
0.25-2 µg/mL | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein corresponding to Human PDE3A |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.1 mg/mL |
Purification |
Affinity Chromatography |
Storage buffer |
PBS, pH 7.2, with 40% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2789661 |
Immunogen sequence: SPQILTPPVI CSSCGRPYSQ GNPADEPLER SGVATRTPSR TDDTAQVTSD YETNNNSDSS DIVQNEDETE CLREPLRKAS ACSTYAPETM MFLDKPILAP EPLVMDNLDS IMEQLNT
Cyclic nucleotide phosphodiesterases (PDEs) comprise a complex group of enzymes, and at least 5 major PDE families or classes with distinctive properties have been identified. Members of the cGMP-inhibited cAMP PDE (cGI-PDE) family, such as PDE3A, are characterized by high affinity for cAMP and cGMP and competitive inhibition of their cAMP hydrolytic activity by cGMP and certain positive inotropic agents (Meacci et al., 1992 [PubMed 1315035]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cAMP phosphodiesterase, myocardial cGMP-inhibited; CGI-PDE A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A; Cyclic GMP-inhibited phosphodiesterase A; phosphodiesterase 3A, cGMP-inhibited
Gene Aliases: CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB; PDE3A
UniProt ID: (Human) Q14432
Entrez Gene ID: (Human) 5139
Molecular Function:
phosphodiesterase
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