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Proteintech
PDE3B Polyclonal Antibody
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Product Details
25290-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PDE3B Fusion Protein Ag18064 (321-670 aa encoded by BC136565)
Conjugate
Form
Liquid
Concentration
0.31 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: CISREQMIL WDWDLKQWYK PHYQNSGGGN GVDLSVLNEA RNMVSDLLTD PSLPPQVISS LRSISSLMGA FSGSCRPKIN PLTPFPGFYP CSEIEDPAEK GDRKLNKGLN RNSLPTPQLR RSSGTSGLLP VEQSSRWDRN NGKRPHQEFG ISSQGCYLNG PFNSNLLTIP KQRSSSVSLT HHVGLRRAGV LSSLSPVNSS NHGPVSTGSL TNRSPIEFPD TADFLNKPSV ILQRSLGNAP NTPDFYQQLR NSDSNLCNSC GHQMLKYVST SESDGTDCCS GKSGEEENIF SKESFKLMET QQEEETEKKD SRKLFQEGDK WLTEEAQSEQ QTNIEQEVSL DLILVEEYDS L (321-670 aa encoded by BC136565)
Target Information
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CGI-PDE B; CGIP1; CGIPDE1; cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B; Cyclic GMP-inhibited phosphodiesterase B; cyclic nucleotide phosphodiesterase; phosphodiesterase 3B, cGMP-inhibited
Gene Aliases: cGIPDE1; HcGIP1; PDE3B
UniProt ID: (Human) Q13370
Entrez Gene ID: (Human) 5140
angiogenesis
cAMP catabolic process
negative regulation of cell adhesion
signal transduction
negative regulation of angiogenesis
cellular response to insulin stimulus
negative regulation of cell adhesion mediated by integrin
negative regulation of cAMP-mediated signaling
negative regulation of lipid catabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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