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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic cyclic peptide (carboxy-terminal peptide common to all PDE4C proteins).|
|Purification||Antigen affinity chromatography|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-31132 detects PDE4C from human samples.
PA1-31132 has been successfully used in immunoprecipitation, Western blot applications.
The PA1-31132 immunogen is: Synthetic cyclic peptide (carboxy-terminal peptide common to all PDE4C proteins).
Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. Cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. PDE4C is a class IV cAMP-specific PDE (summary by Milatovich et al., 1994 [PubMed 8009369]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
cAMP-specific 3',5'-cyclic phosphodiesterase 4C; DPDE1; MGC126222; PDE21; phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila); phosphodiesterase E1 dunce homolog