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Fabgennix
PDE4D3 Polyclonal Antibody, FITC
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Product Details
PD4D3-FITC
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to unique amino acid sequence on PDE4D3 variant gene.
Conjugate
FITC
FITC
FITC
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
0.5-1.5 mg/mL
Storage conditions
-20°C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
PDE4D3 (Phosphodiesterase 4D, cAMP-specific, isoform 3) is an enzyme encoded by the PDE4D gene, which is located on chromosome 5. PDE4D3 belongs to the PDE4 family, which plays a crucial role in hydrolyzing cyclic AMP (cAMP), thereby regulating intracellular levels of this important signaling molecule. PDE4D3 is integral in modulating cAMP signaling pathways, impacting processes such as cardiac function and inflammation. This isoform of phosphodiesterase has been found to interact within a large protein complex, including Epac1, PKA, and ERK5, which is anchored by mAKAP. Phosphorylation by ERK decreases PDE4D3 activity, leading to local cAMP accumulation and increased activation of cAMP-dependent pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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