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Antibody detects endogenous levels of total PDE7B.
The 3', 5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3', 5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.
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Protein Aliases: 3',5'-cyclic-AMP phosphodiesterase 7B; cAMP-specific 3',5'-cyclic phosphodiesterase 7B; cAMP-specific phosphodiesterase 7B; high-affinity cAMP-specific 3',5'-cyclic phosphodiesterase; MGC88256; rolipram-insensitive phosphodiesterase type 7; RP11-472E5.2
Gene Aliases: bA472E5.1; PDE7B
UniProt ID: (Human) Q9NP56, (Mouse) Q9QXQ1
Entrez Gene ID: (Human) 27115, (Rat) 140929, (Mouse) 29863
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