Invitrogen

PDE9A Polyclonal Antibody

Advanced Verification

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

View all (10) PDE9A antibodies

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Datasheet

Protocols

Questions & Answers

Tech Support

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PDE9A Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of PDE9A in U-2 OS cells using a PDE9A polyclonal antibody (Product # PA5-82432). The analysis shows localization to nucleoplasm & vesicles.

PDE9A Antibody in Immunohistochemistry (IHC) — Immunohistochemical analysis of PDE9A in human prostate and liver tissues using a PDE9A polyclonal antibody (Product # PA5-82432). Corresponding RNA-seq data are presented for the same tissues.

PDE9A Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of PDE9A demonstrates antibody specificity. Immunohistochemical analysis of PDE9A using anti-PDE9A Polyclonal Antibody (Product #PA5-82432), shows significant staining of PDE9A in prostate and shows minimal or weak staining in liver tissues. The relative expression levels of PDE9A within each tissue is shown using RNA-Seq. {RE}

Product Details

PA5-82432

Applications	Tested Dilution	Publications
Immunohistochemistry (Paraffin) (IHC (P))	1:200-1:500	-
Immunocytochemistry (ICC/IF)	0.25-2 µg/mL	-

Product Specifications
Species Reactivity	Human
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Recombinant protein corresponding to Human PDE9A View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.1 mg/mL
Purification	Anitgen affinity chromatography
Storage buffer	PBS, pH 7.2, with 40% glycerol
Contains	0.02% sodium azide
Storage conditions	Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID	AB_2789590

Product Specific Information

Immunogen sequence: ECNIFSNIPP DGFKQIRQGM ITLILATDMA RHAEIMDSFK EKMENFDYSN EEHMTLLKMI LIKCCDISNE VRPMEVAEPW VDCLLEEYFM QSDREKSEGL PVAPFMDRDK VTKATAQIGF IKFVLIPMF

Target Information

The protein encoded by this gene catalyzes the hydrolysis of cAMP and cGMP to their corresponding monophosphates. The encoded protein plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides. Multiple transcript variants encoding several different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CGMP-specific 3',5'-cyclic phosphodiesterase type 9; FLJ90181; High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A; phosphodiesterase PDE9A21

Gene Aliases: HSPDE9A2; PDE9A

UniProt ID: (Human) O76083

Entrez Gene ID: (Human) 5152

Molecular Function: phosphodiesterase

Function(s)

signal transduction positive regulation of cardiac muscle hypertrophy cGMP-mediated signaling cGMP metabolic process cGMP catabolic process

Process(es)

3',5'-cyclic-nucleotide phosphodiesterase activity protein binding metal ion binding 3',5'-cyclic-GMP phosphodiesterase activity

PDE9A Polyclonal Antibody

Product Details

PA5-82432

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

RRID

Product Specific Information

Target Information

References (0)

Bioinformatics

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