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          • Primary Antibodies ›
          • PDGF-A Antibodies

          Invitrogen

          PDGF-A Polyclonal Antibody

          View all (25) PDGF-A antibodies
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          Cite PDGF-A Polyclonal Antibody

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          • Antibody Testing Data (4)
          PDGF-A Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 4

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          PDGF-A Antibody (PA5-99405) in WB

          Western blot analysis of PDGF-A in various samples (Lane 1: mouse brain lysate, Lane 2: mouse muscle lysate, Lane 3: rat spleen lysate, Lane 4: rat liver lysate, Lane 5: rat liver lysates treated with blocking peptide). Samples were incubated with PDGF-A polyclonal antibody (Product # PA5-99405). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Product Details

          PA5-99405

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthesized peptide derived from human PDGFA(Accession P04085), corresponding to amino acid residues R144-L171.
          View immunogen

          Conjugate

          Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          RRID

          AB_2818338

          Target Information

          This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit A, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit B. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Alternative splicing results in multiple transcript variants.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: PDGF A-chain; PDGF subunit A; PDGF-1; platelet derived growth factor, alpha; Platelet-derived growth factor A chain; platelet-derived growth factor A-chain; platelet-derived growth factor alpha chain; Platelet-derived growth factor alpha polypeptide; Platelet-derived growth factor subunit A

          View more View less

          Gene Aliases: PDGF-A; PDGF1; PDGFA; PDGFACP; Rpa1

          View more View less

          UniProt ID: (Human) P04085, (Rat) P28576, (Mouse) P20033

          View more View less

          Entrez Gene ID: (Human) 5154, (Rat) 25266, (Mouse) 18590

          View more View less

          Molecular Function: growth factor

          Function(s)
          MAPK cascade angiogenesis response to hypoxia cell activation hair follicle development positive regulation of mesenchymal cell proliferation platelet degranulation transforming growth factor beta receptor signaling pathway cell-cell signaling positive regulation of cell proliferation response to wounding organ morphogenesis response to inorganic substance negative regulation of phosphatidylinositol biosynthetic process negative regulation of platelet activation regulation of phosphatidylinositol 3-kinase signaling positive regulation of phosphatidylinositol 3-kinase signaling regulation of smooth muscle cell migration cell projection assembly actin cytoskeleton organization extracellular matrix organization positive regulation of cell migration positive regulation of protein autophosphorylation response to estradiol response to retinoic acid regulation of actin cytoskeleton organization positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway wound healing response to drug positive regulation of MAP kinase activity positive regulation of MAPK cascade positive regulation of GTPase activity skin development positive regulation of DNA replication phosphatidylinositol phosphorylation platelet-derived growth factor receptor signaling pathway phosphatidylinositol-mediated signaling positive regulation of fibroblast proliferation lung alveolus development inner ear development regulation of peptidyl-tyrosine phosphorylation negative chemotaxis positive regulation of cell division positive regulation of protein kinase B signaling regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling positive regulation of ERK1 and ERK2 cascade regulation of glomerular mesangial cell proliferation embryonic lung development regulation of DNA biosynthetic process blood coagulation response to organic substance digestive tract development multicellular organism development bone development
          Process(es)
          Ras guanyl-nucleotide exchange factor activity platelet-derived growth factor receptor binding protein binding collagen binding growth factor activity protein homodimerization activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity protein heterodimerization activity platelet-derived growth factor binding
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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